Author name: Ben Bikman

Sex Differences in Ketogenesis: How Hormones Shape Fat Metabolism and Ketone Production

Men and women display distinct patterns in fat metabolism and ketone production, driven by hormonal, enzymatic, and adipose-tissue differences. Estrogen enhances fat mobilization and hepatic ketogenesis, while testosterone favors glycolytic pathways. Recognizing these sex-based distinctions refines how we interpret metabolic data and design nutrition strategies in research and clinical settings.

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The Metabolic Storm of Concussions: How Ketones Protect the Injured Brain

A concussion triggers a metabolic storm inside the brain—disrupting glucose use, impairing mitochondria, and creating oxidative stress. But ketones offer a powerful metabolic alternative: they supply energy efficiently, reduce inflammation, and support recovery at the cellular level. This post explores the mechanisms behind concussion-related energy failure and the emerging evidence on how ketogenic metabolism enhances neuroprotection and healing.

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