Latest Metabolic Classrooms

NAD⁺, NADH, and Insulin Resistance: Why Metabolism Is a Battery Problem

Insulin resistance isn’t just a hormone or calorie problem—it’s a cellular energy problem. Inside your cells, a molecule called NAD⁺ acts like a rechargeable battery ...
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AMPK and mTOR: The Metabolic Master Switches of Aging

Aging isn’t random. At the cellular level, it’s regulated by powerful signaling pathways that determine whether your cells are focused on growth or repair. Two ...
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Nicotine: Separating the Molecule from the Smoke

Prefer to listen without the ads? Become a Ben Bikman Insider. For decades, nicotine has been treated as a scientific villain, largely because of its association ...
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Ben Bikman on Diary of a CEO: Insulin Resistance Explained

Ben Bikman joins the Diary of a CEO podcast to discuss insulin resistance, metabolism, and why insulin plays a central role in human health.
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When Ketones Act Like Hormones: Why BHB Is More Than Fuel

Ketones are more than an alternative fuel. Beta-hydroxybutyrate acts like a hormone—sending signals that reduce inflammation, protect mitochondria, and influence gene expression during fasting, exercise, ...
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Glucagon’s Role in Fat Burning

Glucagon is insulin’s metabolic opposite—but it rarely gets the attention it deserves. While insulin drives energy storage, glucagon signals the body to release and burn ...
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How LPS From the Gut Drives Insulin Resistance

LPS-driven inflammation may be a hidden cause of insulin resistance and fatty liver. In this Metabolic Classroom lecture, Dr. Ben Bikman explains how gut permeability ...
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Male Menopause & Metabolism

Men experience a real hormonal decline called andropause—but unlike female menopause, much of it is driven by metabolism, not age. Here’s how testosterone changes, why ...
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The Fat and Muscle Effects of Omega-3 Fatty Acids

Omega-3s do far more than support heart health. Research shows that the long-chain forms—EPA and DHA—enhance fat burning, improve mitochondrial function, and amplify muscle growth ...
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