Latest Metabolic Classrooms
Ethnicity, Body Fat, and the Size That Matters
March 3, 2026
Why do some lean populations have diabetes rates similar to countries with high obesity? The answer isn’t just body weight — it’s how and where ...
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The Metabolic Effects of Bile: More Than Digestion
February 24, 2026
Bile doesn’t just digest fat. Bile acids act like hormones that regulate liver fat, blood sugar, insulin sensitivity, energy expenditure, and inflammation.
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Heart Health: The Markers That Actually Matter
February 16, 2026
Nearly half of heart attack patients have normal LDL cholesterol. Research shows insulin resistance and the triglyceride-to-HDL ratio may be stronger predictors of cardiovascular risk.
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Extracellular Vesicles and Exercise: Your Body’s Molecular Messaging System
February 10, 2026
Exercise doesn’t just strengthen muscles—it triggers a powerful molecular messaging system. Extracellular vesicles released during exercise deliver signals throughout the body that improve insulin sensitivity, ...
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NAD⁺, NADH, and Insulin Resistance: Why Metabolism Is a Battery Problem
February 3, 2026
Insulin resistance isn’t just a hormone or calorie problem—it’s a cellular energy problem. Inside your cells, a molecule called NAD⁺ acts like a rechargeable battery ...
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AMPK and mTOR: The Metabolic Master Switches of Aging
January 26, 2026
Aging isn’t random. At the cellular level, it’s regulated by powerful signaling pathways that determine whether your cells are focused on growth or repair. Two ...
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Nicotine: Separating the Molecule from the Smoke
January 12, 2026
Prefer to listen without the ads? Become a Ben Bikman Insider. For decades, nicotine has been treated as a scientific villain, largely because of its association ...
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Ben Bikman on Diary of a CEO: Insulin Resistance Explained
January 10, 2026
Ben Bikman joins the Diary of a CEO podcast to discuss insulin resistance, metabolism, and why insulin plays a central role in human health.
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When Ketones Act Like Hormones: Why BHB Is More Than Fuel
January 5, 2026
Ketones are more than an alternative fuel. Beta-hydroxybutyrate acts like a hormone—sending signals that reduce inflammation, protect mitochondria, and influence gene expression during fasting, exercise, ...
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