Latest Metabolic Classrooms

Ethnicity, Body Fat, and the Size That Matters

Why do some lean populations have diabetes rates similar to countries with high obesity? The answer isn’t just body weight — it’s how and where ...
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The Metabolic Effects of Bile: More Than Digestion

Bile doesn’t just digest fat. Bile acids act like hormones that regulate liver fat, blood sugar, insulin sensitivity, energy expenditure, and inflammation.
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Heart Health: The Markers That Actually Matter

Nearly half of heart attack patients have normal LDL cholesterol. Research shows insulin resistance and the triglyceride-to-HDL ratio may be stronger predictors of cardiovascular risk.
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Extracellular Vesicles and Exercise: Your Body’s Molecular Messaging System

Exercise doesn’t just strengthen muscles—it triggers a powerful molecular messaging system. Extracellular vesicles released during exercise deliver signals throughout the body that improve insulin sensitivity, ...
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NAD⁺, NADH, and Insulin Resistance: Why Metabolism Is a Battery Problem

Insulin resistance isn’t just a hormone or calorie problem—it’s a cellular energy problem. Inside your cells, a molecule called NAD⁺ acts like a rechargeable battery ...
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AMPK and mTOR: The Metabolic Master Switches of Aging

Aging isn’t random. At the cellular level, it’s regulated by powerful signaling pathways that determine whether your cells are focused on growth or repair. Two ...
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Nicotine: Separating the Molecule from the Smoke

Prefer to listen without the ads? Become a Ben Bikman Insider. For decades, nicotine has been treated as a scientific villain, largely because of its association ...
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Ben Bikman on Diary of a CEO: Insulin Resistance Explained

Ben Bikman joins the Diary of a CEO podcast to discuss insulin resistance, metabolism, and why insulin plays a central role in human health.
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When Ketones Act Like Hormones: Why BHB Is More Than Fuel

Ketones are more than an alternative fuel. Beta-hydroxybutyrate acts like a hormone—sending signals that reduce inflammation, protect mitochondria, and influence gene expression during fasting, exercise, ...
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